Difference between revisions of "VolCT - Group 1B"
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*** Subgroup Analyses: (a) Based on Measureable/Non-Measureable lesions identified by Mike O'Neal of CoreLabs; (b) Difficult, Moderate and Easy as Identified by Mike McNitt-Gray | *** Subgroup Analyses: (a) Based on Measureable/Non-Measureable lesions identified by Mike O'Neal of CoreLabs; (b) Difficult, Moderate and Easy as Identified by Mike McNitt-Gray | ||
− | * Progress Reports | + | * '''Progress Reports''' |
*[[Media:Update Group 1B 4-19-2011-Dr-McNitt-Gray.pdf|QIBA CT Volumetrics,Group 1B:(Patient Image Datasets), 4.19.2011 - Dr. McNitt-Gray]] | *[[Media:Update Group 1B 4-19-2011-Dr-McNitt-Gray.pdf|QIBA CT Volumetrics,Group 1B:(Patient Image Datasets), 4.19.2011 - Dr. McNitt-Gray]] | ||
− | * Analysis Reports | + | * '''Analysis Reports''' |
*[[Media:QIBA_Exp1B_CoffeeBreak_Descriptive_Statistics_24Sep10.pdf |Exp 1B Coffee Break Descriptive Statistics - 24Sep2010]] | *[[Media:QIBA_Exp1B_CoffeeBreak_Descriptive_Statistics_24Sep10.pdf |Exp 1B Coffee Break Descriptive Statistics - 24Sep2010]] | ||
− | |||
*[[Media:QIBA_Exp1B_CoffeeBreak_summary_Table_26Jan11_RECIST_Measureable_or_NOT.pdf |QIBA_Exp1B_Coffee Break Summary Table_26Jan11_RECIST_Measureable_or_NOT]] | *[[Media:QIBA_Exp1B_CoffeeBreak_summary_Table_26Jan11_RECIST_Measureable_or_NOT.pdf |QIBA_Exp1B_Coffee Break Summary Table_26Jan11_RECIST_Measureable_or_NOT]] | ||
+ | *[[Media:QIBA_Exp1B_CoffeeBreak_Descriptive_Statistics_25Mar11_SUBJ_Assess_EZ_Mod_Diff.pdf |Exp 1B Coffee Break Descriptive Statistics - 25Mar2011_Subjective Assessments_EZ_mod_diff]]** | ||
*[[Media:QIBA_Exp1B_CoffeeBreak_summaryTable_minmumDect_18Apr11.pdf|QIBA_Exp1B_CoffeeBreak_summaryTable_minimum Detectable Change_ 18Apr2011]] | *[[Media:QIBA_Exp1B_CoffeeBreak_summaryTable_minmumDect_18Apr11.pdf|QIBA_Exp1B_CoffeeBreak_summaryTable_minimum Detectable Change_ 18Apr2011]] | ||
− | * Methods Related Documents | + | * '''Methods Related Documents''' |
*[[Media:QIBA_Exp1B_CoffeeBreak_lesion_UCLA_version_detailsv3-2_GK_noCTimges.xls|QIBA_Exp1b_Coffee_Break_List of lesions with coordinates and pictures]] | *[[Media:QIBA_Exp1B_CoffeeBreak_lesion_UCLA_version_detailsv3-2_GK_noCTimges.xls|QIBA_Exp1b_Coffee_Break_List of lesions with coordinates and pictures]] | ||
*[[Media:Naming Convention QIBA 1B Experiment 2 26Aug09.xls|Naming Convention for the QIBA Group 1B Experiment and randomization scheme]] | *[[Media:Naming Convention QIBA 1B Experiment 2 26Aug09.xls|Naming Convention for the QIBA Group 1B Experiment and randomization scheme]] | ||
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*[[Vol-CT - 1B Group Call Summaries]] | *[[Vol-CT - 1B Group Call Summaries]] | ||
* | * | ||
− | * Other Related Documents | + | * '''Other Related Documents''' |
* Related Profile: [[CT_Lung_Nodule_Volume_Quantification_Profile#Activity:_Measurement| Lung Vol Quantification - Measurement Activity]] | * Related Profile: [[CT_Lung_Nodule_Volume_Quantification_Profile#Activity:_Measurement| Lung Vol Quantification - Measurement Activity]] | ||
Revision as of 05:24, 20 April 2011
Current Goals & Status:
- Question: What is the minimum detectable level of change in patient datasets under a “No Change” condition?
- AIMS: For patient datasets acquired over a very short time interval (“no change” condition”) investigate variance in measuring change in volume, diameter and bi-directional diameters of lesions
- Investigate inter-observer variability in each task
- Investigate Intra-observer variability in each task
- Methods - Materials
- Image Data from MSK Coffee Break Experiment
- 32 NSCLC patients, imaged twice on same scanner over period < 15 minutes
- Thin slice (1.25 mm thick) image data
- Selected one lesion per patient
- no outcome data
- Publicly Available on NCIA
- Methods - Materials
- Methods - Readings
- 5 readers
- Read CT at timepoint 1, CT at timepoint 2 and repeat either CT timepoint 1 or timeoint 2 to assess intra-reader variability
- Methods - Measurements
- Measure Single Longest Diameter, manually (SLD)
- Measure Longest Diameter and Perpendicular Diameter; take product to obtain Product of Diameters (POD)
- Contour Full Boundary of lesion with semiautomated tool; calculate volume (Vol)
- Extract other measures as well (SLD from POD measureement; SLD from VOl and POD from Vol).
- The Order of Readers, Lesions and Measurement Methods were Randomized (Measurements done in Blocks of 10)
- Methods - Readings
- Analyses
- Pooled Analysis across readers and lesions; Percent Difference between Scan 1 and Scan 2 for each measurement method
- Subgroup Analyses: (a) Based on Measureable/Non-Measureable lesions identified by Mike O'Neal of CoreLabs; (b) Difficult, Moderate and Easy as Identified by Mike McNitt-Gray
- Analyses
- Analysis Reports
- Exp 1B Coffee Break Descriptive Statistics - 24Sep2010
- QIBA_Exp1B_Coffee Break Summary Table_26Jan11_RECIST_Measureable_or_NOT
- Exp 1B Coffee Break Descriptive Statistics - 25Mar2011_Subjective Assessments_EZ_mod_diff**
- QIBA_Exp1B_CoffeeBreak_summaryTable_minimum Detectable Change_ 18Apr2011
- Methods Related Documents
- QIBA_Exp1b_Coffee_Break_List of lesions with coordinates and pictures
- Naming Convention for the QIBA Group 1B Experiment and randomization scheme
- Vol-CT - 1B Group Call Summaries
- Other Related Documents
- Related Profile: Lung Vol Quantification - Measurement Activity
- Proposed Group 1B Questions & Datases (2009-02-10) -- Feedback Welcome -- Dr. McNitt-Gray
- ACRIN 6678 Quality Control Parameters for CT Scan Tumor Volumetric Measurements
- Conference Paper on Reproducibility and Accuracy of Uni- and Bi-Dimensional Tumor Measurements from MRI and CT Volumes, which looks at RECIST, WHO and Volume measurements.