Claim Language/Detail

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Proposed Lung Density Claim for COPD/Asthma Profile

Following this profile is expected to provide long term instrumental precision (coefficient of variation) of bulk lung density of 3%. Consequently, 2 measurements separated by 3 years will detect a 2.8% change per year with a 95% confidence if long term instrumental precision limits detection of change of lung density using CT.


  • There is a strong desire to have the specs provide an outcomes measure over two years based on NIH via SPIROMICS (Dr. Hoffman)