VolCT - Group 1B

Current Goals & Status:

• Question: What is measurement variation for different software/user methods for a reference set of image data?
  • Intra-rater reliability, i.e., test-retest precision for pre-specified tumors (a.k.a. "marked up") by single image analysis operators
  • Ground Truth: Pooled from all image analyses meeting quality criteria to estimate confidence intervals around "true" volume.
  • Approach: Patient Change Data from RIDER Database:
    • > 300 cases as of Sept 2008
    • Most with multiple time points
    • Few with thin slice (<1.5 mm thick) image data
    • No contours provided (user has to provide their own as part of measurement)
    • no outcome data
    • Publicly Available on NCIA
• Related Profile: Lung Vol Quantification - Measurement Activity

• Vol-CT - 1B Group Call Summaries

• Proposed Group 1B Questions & Datases (2009-02-10) -- Feedback Welcome -- Dr. McNitt-Gray
• ACRIN 6678 Quality Control Parameters for CT Scan Tumor Volumetric Measurements

• Conference Paper on Reproducibility and Accuracy of Uni- and Bi-Dimensional Tumor Measurements from MRI and CT Volumes, which looks at RECIST, WHO and Volume measurements.