Difference between revisions of "VolCT - Group 1B"

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*[[Media:ACRIN 6678 QC Parmeters for CT Scan Measurements.pdf|ACRIN 6678 Quality Control Parameters for CT Scan Tumor Volumetric Measurements]]
 
*[[Media:ACRIN 6678 QC Parmeters for CT Scan Measurements.pdf|ACRIN 6678 Quality Control Parameters for CT Scan Tumor Volumetric Measurements]]
  
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* [http://www.virtualscopics.com/pdf/ConferencePapers/Ashton_Manchester.pdf Conference Paper] on Reproducibility and Accuracy of Uni- and Bi-Dimensional Tumor Measurements from MRI and CT Volumes, which looks at RECIST, WHO and Volume measurements.
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* [https://web.archive.org/web/20110206162336/http://www.virtualscopics.com/pdf/ConferencePapers/Ashton_Manchester.pdf Conference Poster] on Reproducibility and Accuracy of Uni- and Bi-Dimensional Tumor Measurements from MRI and CT Volumes, which looks at RECIST, WHO and Volume measurements.
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* '''Final Report'''
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*[http://dx.doi.org/10.1016/j.tranon.2015.01.001 McNitt-Gray et al. Determining the Variability of Lesion Size Measurements from CT Patient Data Sets Acquired under “No Change” Conditions]
  
 
==Downloadable Images and [[:Category:Datasets|Data Sets]]==
 
==Downloadable Images and [[:Category:Datasets|Data Sets]]==

Revision as of 12:59, 29 September 2020

Current Goals & Status:

Question: What is the minimum detectable level of change in patient datasets under a “No Change” condition?

    • AIMS: For patient datasets acquired over a very short time interval (“no change” condition”) investigate variance in measuring change in volume, diameter and bi-directional diameters of lesions
    • Investigate inter-observer variability in each task
    • Investigate Intra-observer variability in each task
    • Methods - Materials
      • Image Data from MSK Coffee Break Experiment
      • 32 NSCLC patients, imaged twice on same scanner over period < 15 minutes
      • Thin slice (1.25 mm thick) image data
      • Selected one lesion per patient
      • no outcome data
      • Publicly Available on NCIA
    • Methods - Readings
      • 5 readers
      • Read CT at timepoint 1, CT at timepoint 2 and repeat either CT timepoint 1 or timeoint 2 to assess intra-reader variability
    • Methods - Measurements
      • Measure Single Longest Diameter, manually (SLD)
      • Measure Longest Diameter and Perpendicular Diameter; take product to obtain Product of Diameters (POD)
      • Contour Full Boundary of lesion with semiautomated tool; calculate volume (Vol)
      • Extract other measures as well (SLD from POD measureement; SLD from VOl and POD from Vol).
    • The Order of Readers, Lesions and Measurement Methods were Randomized (Measurements done in Blocks of 10)
    • Analyses
      • Pooled Analysis across readers and lesions; Percent Difference between Scan 1 and Scan 2 for each measurement method
      • Subgroup Analyses: (a) Based on Measureable/Non-Measureable lesions identified by Mike O'Neal of CoreLabs; (b) Difficult, Moderate and Easy as Identified by Mike McNitt-Gray
  • Conference Poster on Reproducibility and Accuracy of Uni- and Bi-Dimensional Tumor Measurements from MRI and CT Volumes, which looks at RECIST, WHO and Volume measurements.

Downloadable Images and Data Sets

Round 2 Images and Results

Round 1 Images and Results

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