PET Amyloid Biomarker Ctte

Co-chairs: Satoshi Minoshima, MD, PhD; Eric S. Perlman, MD; Anne M. Smith, PhD

Secretary: Julie Lisiecki

Roster: (Roster)

Project Snapshot

There is a draft Profile, and current outline of the Claim is:

• SUVr will be the measurand
• The claim will have two components

1) Cross-sectional: single subject scan

2) Longitudinal: following subject over time

Due to the complexity of having multiple PET Amyloid tracers, a subgroup, the Test-retest Group, has been formed including academics and industry representatives from all of the major PET Amyloid tracer vendors. This group will evaluate the published data on amyloid imaging precision, to determine what level of precision can be claimed in the Profile. The committee’s goal is to have a final draft Profile by December, 2015.

Collaborations: RSNA QIBA is now an affiliate of GAAIN (Global Alzheimer’s Association International Network)

PET Amyloid Meetings/Call Summaries

• QIBA PET Amyloid Biomarker Committee Call Summaries

PET Amyloid Profile Development

• QIBA PET-Amyloid DRAFT Profile with tracked changes {Dr. Perlman} July 7, 2016 (PDF)

• QIBA PET-Amyloid DRAFT Profile with tracked changes {Dr. Perlman} April 26 - May 5, 2016

• QIBA PET-Amyloid DRAFT Profile with tracked changes {Dr. Perlman} March 28, 2016

Reference Materials

Presentations and Reports:

• 08 12 2016 QIBA PET Amyloid Biomarker Committee Presentation Slides - presented by Dr. Smith
• 2015-PET-Amyloid DRO Report – Drs. Pierce, Haynor, Sunderland, and Kinahan - Discussed on 08 12 2016 WebEx
• Conformance Formulae - Discussed on 08 12 2016 WebEx
• QIBA Conformance Draft - Discussed on 08 12 2016 WebEx

• 03 11 2016 QIBA PET Amyloid Biomarker Committee Presentation Slides - presented by Dr. Smith

• 02 13 2015 QIBA PET Amyloid Biomarker Committee Presentation Notes - presented by Dr. Perlman