Lung Density Biomarker Ctte

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Co-chairs: Sean Fain, PhD; Matthew Fuld, PhD; David Lynch, MD
Secretary: Julie Lisiecki


Scope: Quantitative CT lung densitometry and morphology for COPD and related diseases.

Initial Objectives:

  • Characterize the precision and accuracy of phenotyping and progression measurements in emphysema and asthma.
This is an essential effort to classify phenotype and assess longitudinal changes as medically meaningful surrogates for health status.
  • Compare the sensitivity of CT measurements to spirometry and other accepted measures.
This will be necessary in order to determine if Progressive Disease can be detected significantly sooner with quantitative imaging techniques than with currently accepted methods.

Recent Meetings/Call Summaries

Lung Density/COPD BC Call Summaries Archive

Profile Development

Status - <summarize current status>

Archive - Lung Density

Protocol Development Activities

Groundwork Activities

Validate key concepts and answer key questions needed to write the Profiles and demonstrate their effectiveness.

  • Phantom project

Working Documents

Reference Documents

Round 2 of QIBA Funded Projects