CT Volumetry Biomarker Ctte
- Co-chairs: Gregory Goldmacher, MD, PhD, MBA; Jenifer Siegelman, MD, MPH; Ehsan Samei, PhD
- Secretary: Julie Lisiecki
- Tcons are held roughly Weekly. Contact the secretary for details.
- Call Summaries
Advanced Disease/Tumor Volume Change Profile
Status - Consensus Profile complete
- QIBA Profile: CT Tumor Volume Change Profile CONSENSUS 2016.11.21b
- Checklist - CT Tumor Volumetry for Advanced Disease Field Trial v1.0
Status - Technical Confirmation in progress
- CT Tumor Volume Change Profile - PostConsensus DRAFT 2017.04.03
- Technical Confirmation Results and Resolutions - ONGOING WORK
- Columbia Volume repeatability assessment - Coming Soon
Past and Future
Lung Nodule Assessment in CT Screening Profile
Status - Vote for consensus at the CT Volumetry BC level underway
Status - A 2nd Round of Public Comment is currently underway *QIBA Lung Nodule Profile 15May2017
Status - Public Comment complete
- QIBA Profile: CT Lung Nodule Assessment in Screening Public Comment 2016.06.01 (ended Sept 2016)
Status - Consensus in progress
- QIBA Lung Nodule Profile Draft 2017.08.02
- Comments on mid-May draft from Kevin 2017.06.06
- Review and comments from physics subgroup on proposed Assessment Procedures 2017.08.07
- Additional working drafts may be available on the Small Lung Nodule TF page
- Archived Versions of Profile-related documents.
These projects investigate (and resolve) scientific questions underlying QIBA Profile work.
- VolCT - Group 1A - Analyze Bias/Variance where Ground Truth is Known Deterministically
- VolCT - Group 1B - Focus on Volume Change Analysis of Pulmonary Nodules in Diagnostic Settings
- VolCT - Group 1C - Model Sources of Variability from a Systems Engineering Analysis
- VolCT - Group 3A - Characterize variability due to algorithms (using phantoms / clinical data)
- VolCT - Group 3B - Characterize clinical utility/efficacy with respect to clinical endpoints
- VolCT - Colorado Group - Quantifying variability in measurement of pulmonary nodule
- NIBIB-2 Proposal for CT Volumetry16-APR-2012
- Dr Mulshine's Presentation Materials from July 2nd adapted from the ATCC Website
- "Why QIBA?" - Specifics associated with CT device and software manufacturers.
- Dr Petrick's 2011 SPIE Presentation Materials
- “Evaluation of 1D, 2D and 3D nodule size estimation by radiologists for spherical and non-spherical nodules through CT thoracic phantom imaging” - Talk
- “Evaluation of 1D, 2D and 3D nodule size estimation by radiologists for spherical and non-spherical nodules through CT thoracic phantom imaging” - Paper
- Compliance Documents: QIBA Approach to Compliance-- Andrew J. Buckler, MS, Program Director, QIBA 08.15.11
- Are we ready? A time for measurement of physiological parameters of the lung using multidetector row CT scans. Hatabu H. Acad Radiol. 2009 Mar; 16(3):249. Academic Radiology
- Radiology 2007 - Coronary Calcium Scoring - This paper by Dr. McCollough et al is may be seen to be analaogous to our work in that it addresses similar issues (e.g. achieving "standard" noise levels). It could be thought of as an early draft of a Calcium Scoring profile, including both groundwork and equipment specifications.
- Helical multidetector row quantitative computed tomography (QCT) precision. Bligh M, Bidaut L, White RA, Murphy WA Jr, Stevens DM, Cody DD. Acad Radiol. 2009 Feb; 16(2):150-9. Academic Radiology
- Comparison of the accuracy of CT volume calculated by circumscription to prolate ellipsoid volume (bidimensional measurement multiplied by coronal long axis). Rkein AM, Harrigal C, Friedman AC, Persky D, Krupinski E. Acad Radiol. 2009 Feb; 16(2):181-6. Academic Radiology
QIBA Funded Projects
- Duke University
- Columbia University Medical Center
- University of Colorado Denver, Department of Radiology
- David Geffen School of Medicine at UCLA, Department of Radiology
- CoreLab Partners, Inc.