CT Volumetry Biomarker Ctte

Project Snapshot

• Work Breakdown for Volumetric CT 07.12.10
• Validation Roadmap - P. David Mozley, MD
• Thoughts on the QIBA Process: Profiles, UPICT & Measurements by Kevin O’Donnell-20090629

Meetings / Call Summaries

• Call Summaries

Profile Development

• VIA Profile v1.5 01-09-2011
• VIA Protocol v1.4 9-11-2010
• UPICT Template for CT Lung Neoadjuvant WoOp Protocol V0.2 Posted 12/2009
• Profile: CT Lung Nodule Volume Measurement for Primary/Regional Nodes and Metastatic Sites Last updated 6/2009
• Profile: CT Lung Nodule Volume Change for Primary, Hilar and Medistinal Lymph Nodes
• Profile: CT Lung Nodule Response
• Profile: CT Lung Nodule - Small Nodule in Neoadjuvant Setting
• UPICT Template for CT Lung Nodule Protocol Work in Progress

Working Documents

• Profile Strategy for Vol CT
• VolCT - Group 1A - Analyze Bias/Variance where Ground Truth is Known Deterministically
• VolCT - Group 1B - Focus on Volume Change Analysis of Pulmonary Nodules in Diagnostic Settings
• VolCT - Group 1C - Model Sources of Variability from a Systems Engineering Analysis
• VolCT - Group 2 - Set Standards for using Volumetric Imaging in Clinical Trials
• Sources of Variability - Andrew Buckler
• Quantification in Imaging-Dr Dirk Colditz August 23, 2010
• 2009 12 31 Review of Volumetric Image Analysis in Patients with Solid Tumors - long version
• Initial Target Selection - describing the early prioritization discussions and settling on Lung Tumor Volumes

See the Datasets page of the QIBA Resource Catalog

Reference Materials

• Are we ready? A time for measurement of physiological parameters of the lung using multidetector row CT scans. Hatabu H. Acad Radiol. 2009 Mar; 16(3):249. Academic Radiology
• Radiology 2007 - Coronary Calcium Scoring - This paper by Dr. McCollough et al is may be seen to be analaogous to our work in that it addresses similar issues (e.g. achieving "standard" noise levels). It could be thought of as an early draft of a Calcium Scoring profile, including both groundwork and equipment specifications.
• Helical multidetector row quantitative computed tomography (QCT) precision. Bligh M, Bidaut L, White RA, Murphy WA Jr, Stevens DM, Cody DD. Acad Radiol. 2009 Feb; 16(2):150-9. Academic Radiology
• Comparison of the accuracy of CT volume calculated by circumscription to prolate ellipsoid volume (bidimensional measurement multiplied by coronal long axis). Rkein AM, Harrigal C, Friedman AC, Persky D, Krupinski E. Acad Radiol. 2009 Feb; 16(2):181-6. Academic Radiology
• What Are Profiles?