Difference between revisions of "CT Volumetry Biomarker Ctte"

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* [[Media:Ref6_Avila_etal_WCTIHotTopicAbstract.pdf|Ref6_Avila_etal_WCTI Hot Topic Abstract]]   
* [[Media:Ref6_Avila_etal_WCTIHotTopicAbstract.pdf|Ref6_Avila_etal_WCTI Hot Topic Abstract]]   
* [[Media:Ref7__Avila_etal_ANovel UltraLowCostCTImageQualityMeasurementDev.pdf|Ref7__Avila_et al_A Novel Ultra Low Cost CT Image Quality Measurement Dev]]   
* [[Media:Ref7__Avila_etal_ANovel UltraLowCostCTImageQualityMeasurementDev.pdf|Ref7__Avila_et al_A Novel Ultra Low Cost CT Image Quality Measurement Dev]]   
* [[Media:Automatic Estimation of Measurement Error on CT Imaging.pdf|Avila et al. Automatic Estimation of Measurement Error on CT Imaging]] "question 8"
* [[Ref8_Avila_etal_AutomaticEstimationofMeasurementErroronCT Imaging.pdf|Ref8_Avila_et al_Automatic Estimation of Measurement Error on CT Imaging]]

Revision as of 18:54, 9 October 2017

Co-chairs: Gregory Goldmacher, MD, PhD, MBA; Jenifer Siegelman, MD, MPH; Ehsan Samei, PhD
Secretary: Julie Lisiecki


  • Tcons are held roughly Weekly. Contact the secretary for details.
  • Call Summaries

Profile Development

Advanced Disease/Tumor Volume Change Profile

Status - Consensus Profile complete

Status - Technical Confirmation in progress

  • Columbia Volume repeatability assessment - Coming Soon

Past and Future

Lung Nodule Assessment in CT Screening Profile

Status - Final Review in progress

Supporting documents:

Status - Public Comment complete


Groundwork Projects

These projects investigate (and resolve) scientific questions underlying QIBA Profile work.

  • VolCT - Group 1A - Analyze Bias/Variance where Ground Truth is Known Deterministically
  • VolCT - Group 1B - Focus on Volume Change Analysis of Pulmonary Nodules in Diagnostic Settings
  • VolCT - Group 1C - Model Sources of Variability from a Systems Engineering Analysis
  • VolCT - Group 3A - Characterize variability due to algorithms (using phantoms / clinical data)
  • VolCT - Group 3B - Characterize clinical utility/efficacy with respect to clinical endpoints
  • VolCT - Colorado Group - Quantifying variability in measurement of pulmonary nodule

Reference Materials




Reference Articles

  • Are we ready? A time for measurement of physiological parameters of the lung using multidetector row CT scans. Hatabu H. Acad Radiol. 2009 Mar; 16(3):249. Academic Radiology
  • Radiology 2007 - Coronary Calcium Scoring - This paper by Dr. McCollough et al is may be seen to be analaogous to our work in that it addresses similar issues (e.g. achieving "standard" noise levels). It could be thought of as an early draft of a Calcium Scoring profile, including both groundwork and equipment specifications.
  • Helical multidetector row quantitative computed tomography (QCT) precision. Bligh M, Bidaut L, White RA, Murphy WA Jr, Stevens DM, Cody DD. Acad Radiol. 2009 Feb; 16(2):150-9. Academic Radiology
  • Comparison of the accuracy of CT volume calculated by circumscription to prolate ellipsoid volume (bidimensional measurement multiplied by coronal long axis). Rkein AM, Harrigal C, Friedman AC, Persky D, Krupinski E. Acad Radiol. 2009 Feb; 16(2):181-6. Academic Radiology

QIBA Funded Projects

Round 1

Round 2