Difference between revisions of "Archived "What is a Profile?" description as of 08.19.2011"

From QIBA Wiki
Jump to navigation Jump to search
(New page: __NOTOC__ This Wiki is for collaborative creation of QIBA materials and ongoing activities. ='''Quantitative Imaging Biomarkers Alliance (QIBA)'''= '''QIBA Mission: Improve the value and...)
 
Line 1: Line 1:
__NOTOC__
+
____NOTOC__
This Wiki is for collaborative creation of QIBA materials and ongoing activities.
+
* A Profile is a document.
  
='''Quantitative Imaging Biomarkers Alliance (QIBA)'''=
 
  
'''QIBA Mission: Improve the value and practicality of quantitative biomarkers by reducing variability across devices, patients and time.'''
+
* It tells a user what can be accomplished by following the Profile. ("Profile Claims")
 +
: E.g. you will be able to detect volume changes of greater than <20%> in Stage IV Lung Nodules which are <5mm> in diameter or greater.  
  
  
QIBA is an initiative to advance quantitative imaging and the use of imaging biomarkers in clinical trials and clinical practice by engaging researchers, healthcare professionals and industry .  This involves:
+
* It tells a vendor what they must implement in their product to state compliance with the Profile. ("Profile Details")
 +
: E.g. to comply, the scanner must be able to:
 +
::* scan a <Mark-324> Chest Phantom, identify the smallest resolvable target, display the diameter of that target
 +
::* demonstrate resolving targets at least as small as <2mm> diameter on the Mark-324 phantom
 +
::* scan patients according to the ACRIN NLST acquisition protocol
 +
: E.g. to comply, the quantification application must be able to:
 +
::* segment a nodule (automatically or manually), derive the volume, store it in a DICOM object
 +
::* run a user through a set of test data with known volumes and at the end display an accuracy score
  
:* collaborating to identify needs, barriers, and solutions to develop and test consistent, reliable, valid, and achievable quantitative imaging results across imaging platforms, clinical sites, and time.
 
:* accelerating the development and adoption of hardware and software standards needed to achieve accurate and reproducible quantitative results from imaging methods.
 
  
 +
* It may also tell the user staff what they must do for the Profile Claims to be realized. ("Profile Details")
 +
: E.g. to comply, the site CT techs must be able to:
 +
::* scan the patient within 10 minutes of contrast injection
 +
: E.g. to comply, the radiologist must be able to:
 +
::* achieve a score of <95%> or better using their segmentation application on the <Lung Invaders> test set.
  
QIBA develops Profile specifications and coordinates the necessary research and qualification groundwork.
 
:* [[What Are Profiles?]]
 
:* [[Media:Profiling.ppt|How Does QIBA Derive Profiles?]]
 
  
==QIBA Committees==
+
==How do Profiles fit in the IHE Process?==
QIBA currently has five active technical committees:
 
:* [[DCE-MRI tech ctte]]
 
:* [[fMRI tech ctte]]
 
:* [[FDG-PET tech ctte]]
 
:* [[Volumetric-CT tech ctte]]
 
:* [[COPD-Asthma tech ctte]]
 
  
==Documents==
+
The Profile concept and process has been borrowed from '''[http://wiki.ihe.net IHE]'''
*[[Media:QIBA Round-1 Projects Overview.pdf|QIBA Round-1 Funded Projects Overview]]
 
*[[Media:HHSN268201000050C_QIBA_Semiannual_Report_3-11-2010.doc|QIBA 1H-FY2011 Semi-annual Report (2011.03.11)]]
 
*[[Media:Why_QIBA_CT_specifics.pdf|"Why QIBA?" - Specifics associated with CT device and software manufacturers.]]
 
*[[Media:Why_QIBA_PET-CT_specifics.pdf|"Why QIBA?" - Specifics associated with PET-CT device and software manufacturers.]]
 
*[[Media:Why_QIBA_MR_specifics.pdf|"Why QIBA?" - Specifics associated with MR device and software manufacturers.]]
 
*[[Media:HHSN268201000050C_QIBA_Proposed_Workplan_11-22-2010.doc|QIBA Work Plan (2010.11.22)]]
 
*[[QIBA and UPICT posters from RSNA 2010 Annual Meeting]]
 
*[[QIBA and UPICT posters from RSNA 2009 Annual Meeting]]
 
*[[Media:EU.2009.08.04 Guideline on Clinical evaluation of diagnostic agents.pdf|EMEA Guideline on Clinical Evaluation of Diagnostic Agents (2009.08.04)]]
 
*[[Media:EU.2009.08.04 Appendix 1 to the guideline.pdf|EMEA Guideline - Appendix 1 (2009.08.04)]]
 
*[[Media:Oncology section.ppt|Oncology section from 2009 Imaging Biomarkers Roundtable]]
 
*[[Media:FREEMAN_FINAL_PROOF.pdf|QIBA posters from RSNA 2008 Annual Meeting]]
 
  
 +
* Users identify a high priority multi-system problem.
  
==Public Comment Documents==
+
* Vendors & Users collaborate to document a standards-based solution (a Profile).
  
:*[[Work Product for Review]]
+
* Vendors confirm it works by testing their implementations with other vendors (a Connectathon)
  
==Ad Hoc Committees==
 
:*[[Committee on Open Image Archives]]
 
  
----
+
==How does QIBA differ from IHE?==
  
==Quantitative Imaging/Imaging Biomarkers and QIBA Meetings and Activities==
+
* IHE mostly profiles engineering problems. QIBA also tackles scientific problems.
*QI/IB Special Interest Session-
 
Imaging Biomarkers for Clinical Care and Research
 
Monday, November 29, 2010
 
'''[http://www2.rsna.org/re/QI_IB_Special_Interest_Session_RSNA_2010/Index.htm Presentations]'''
 
  
*QIBA Annual Meeting Presentations
+
* When a profile claim is unvalidated or a profile detail cannot be defined until further research is done:  
May 24-25, 2011
+
** IHE declares the profile premature and sets it aside until such groundwork is completed
Renaissance Arlington Capital View, Arlington VA
+
** QIBA locates, encourages, and if necessary coordinates, getting the research completed so the profile can proceed
'''[http://www2.rsna.org/re/QIBA_Annual_Meeting_2011/ Presentations]'''
 
 
 
 
 
----
 
 
 
NEW: '''[[How To's| "How To" help pages]]'''
 
 
 
*[[Media:Enabling E-alerts-20100504.pdf|Enabling E-alerts]]
 
 
 
*[[Media:Microsoft Word - WIKI PROTOCOL-v2.pdf|Posting Material]]
 
 
 
*[[Media:Wiki Help-History Overview2.pdf|History Search]]
 
 
 
'''''<This Wiki is a Work In Progress:  read [[Help:Contents|Help]], create an [[Wiki Accounts|account]], contribute>'''''
 

Revision as of 22:04, 19 August 2011

__

  • A Profile is a document.


  • It tells a user what can be accomplished by following the Profile. ("Profile Claims")
E.g. you will be able to detect volume changes of greater than <20%> in Stage IV Lung Nodules which are <5mm> in diameter or greater.


  • It tells a vendor what they must implement in their product to state compliance with the Profile. ("Profile Details")
E.g. to comply, the scanner must be able to:
  • scan a <Mark-324> Chest Phantom, identify the smallest resolvable target, display the diameter of that target
  • demonstrate resolving targets at least as small as <2mm> diameter on the Mark-324 phantom
  • scan patients according to the ACRIN NLST acquisition protocol
E.g. to comply, the quantification application must be able to:
  • segment a nodule (automatically or manually), derive the volume, store it in a DICOM object
  • run a user through a set of test data with known volumes and at the end display an accuracy score


  • It may also tell the user staff what they must do for the Profile Claims to be realized. ("Profile Details")
E.g. to comply, the site CT techs must be able to:
  • scan the patient within 10 minutes of contrast injection
E.g. to comply, the radiologist must be able to:
  • achieve a score of <95%> or better using their segmentation application on the <Lung Invaders> test set.


How do Profiles fit in the IHE Process?

The Profile concept and process has been borrowed from IHE

  • Users identify a high priority multi-system problem.
  • Vendors & Users collaborate to document a standards-based solution (a Profile).
  • Vendors confirm it works by testing their implementations with other vendors (a Connectathon)


How does QIBA differ from IHE?

  • IHE mostly profiles engineering problems. QIBA also tackles scientific problems.
  • When a profile claim is unvalidated or a profile detail cannot be defined until further research is done:
    • IHE declares the profile premature and sets it aside until such groundwork is completed
    • QIBA locates, encourages, and if necessary coordinates, getting the research completed so the profile can proceed