Difference between revisions of "Archived "What is a Profile?" description as of 08.19.2011"

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(New page: __NOTOC__ This Wiki is for collaborative creation of QIBA materials and ongoing activities. ='''Quantitative Imaging Biomarkers Alliance (QIBA)'''= '''QIBA Mission: Improve the value and...)
 
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__NOTOC__
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____NOTOC__
This Wiki is for collaborative creation of QIBA materials and ongoing activities.
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* A Profile is a document.
  
='''Quantitative Imaging Biomarkers Alliance (QIBA)'''=
 
  
'''QIBA Mission: Improve the value and practicality of quantitative biomarkers by reducing variability across devices, patients and time.'''
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* It tells a user what can be accomplished by following the Profile. ("Profile Claims")
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: E.g. you will be able to detect volume changes of greater than <20%> in Stage IV Lung Nodules which are <5mm> in diameter or greater.  
  
  
QIBA is an initiative to advance quantitative imaging and the use of imaging biomarkers in clinical trials and clinical practice by engaging researchers, healthcare professionals and industry . This involves:
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* It tells a vendor what they must implement in their product to state compliance with the Profile. ("Profile Details")
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: E.g. to comply, the scanner must be able to:
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::* scan a <Mark-324> Chest Phantom, identify the smallest resolvable target, display the diameter of that target
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::* demonstrate resolving targets at least as small as <2mm> diameter on the Mark-324 phantom
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::* scan patients according to the ACRIN NLST acquisition protocol
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: E.g. to comply, the quantification application must be able to:
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::* segment a nodule (automatically or manually), derive the volume, store it in a DICOM object
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::* run a user through a set of test data with known volumes and at the end display an accuracy score
  
:* collaborating to identify needs, barriers, and solutions to develop and test consistent, reliable, valid, and achievable quantitative imaging results across imaging platforms, clinical sites, and time.
 
:* accelerating the development and adoption of hardware and software standards needed to achieve accurate and reproducible quantitative results from imaging methods.
 
  
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* It may also tell the user staff what they must do for the Profile Claims to be realized. ("Profile Details")
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: E.g. to comply, the site CT techs must be able to:
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::* scan the patient within 10 minutes of contrast injection
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: E.g. to comply, the radiologist must be able to:
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::* achieve a score of <95%> or better using their segmentation application on the <Lung Invaders> test set.
  
QIBA develops Profile specifications and coordinates the necessary research and qualification groundwork.
 
:* [[What Are Profiles?]]
 
:* [[Media:Profiling.ppt|How Does QIBA Derive Profiles?]]
 
  
==QIBA Committees==
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==How do Profiles fit in the IHE Process?==
QIBA currently has five active technical committees:
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:* [[DCE-MRI tech ctte]]
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:* [[fMRI tech ctte]]
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:* [[FDG-PET tech ctte]]
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:* [[Volumetric-CT tech ctte]]
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:* [[COPD-Asthma tech ctte]]
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==Documents==
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The Profile concept and process has been borrowed from '''[http://wiki.ihe.net IHE]'''
*[[Media:QIBA Round-1 Projects Overview.pdf|QIBA Round-1 Funded Projects Overview]]
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*[[Media:HHSN268201000050C_QIBA_Semiannual_Report_3-11-2010.doc|QIBA 1H-FY2011 Semi-annual Report (2011.03.11)]]
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*[[Media:Why_QIBA_CT_specifics.pdf|"Why QIBA?" - Specifics associated with CT device and software manufacturers.]]
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*[[Media:Why_QIBA_PET-CT_specifics.pdf|"Why QIBA?" - Specifics associated with PET-CT device and software manufacturers.]]
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*[[Media:Why_QIBA_MR_specifics.pdf|"Why QIBA?" - Specifics associated with MR device and software manufacturers.]]
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*[[Media:HHSN268201000050C_QIBA_Proposed_Workplan_11-22-2010.doc|QIBA Work Plan (2010.11.22)]]
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*[[QIBA and UPICT posters from RSNA 2010 Annual Meeting]]
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*[[QIBA and UPICT posters from RSNA 2009 Annual Meeting]]
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*[[Media:EU.2009.08.04 Guideline on Clinical evaluation of diagnostic agents.pdf|EMEA Guideline on Clinical Evaluation of Diagnostic Agents (2009.08.04)]]
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*[[Media:EU.2009.08.04 Appendix 1 to the guideline.pdf|EMEA Guideline - Appendix 1 (2009.08.04)]]
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*[[Media:Oncology section.ppt|Oncology section from 2009 Imaging Biomarkers Roundtable]]
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*[[Media:FREEMAN_FINAL_PROOF.pdf|QIBA posters from RSNA 2008 Annual Meeting]]
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* Users identify a high priority multi-system problem.
  
==Public Comment Documents==
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* Vendors & Users collaborate to document a standards-based solution (a Profile).
  
:*[[Work Product for Review]]
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* Vendors confirm it works by testing their implementations with other vendors (a Connectathon)
  
==Ad Hoc Committees==
 
:*[[Committee on Open Image Archives]]
 
  
----
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==How does QIBA differ from IHE?==
  
==Quantitative Imaging/Imaging Biomarkers and QIBA Meetings and Activities==
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* IHE mostly profiles engineering problems. QIBA also tackles scientific problems.
*QI/IB Special Interest Session-
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Imaging Biomarkers for Clinical Care and Research
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Monday, November 29, 2010
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'''[http://www2.rsna.org/re/QI_IB_Special_Interest_Session_RSNA_2010/Index.htm Presentations]'''
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*QIBA Annual Meeting Presentations
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* When a profile claim is unvalidated or a profile detail cannot be defined until further research is done:  
May 24-25, 2011
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** IHE declares the profile premature and sets it aside until such groundwork is completed
Renaissance Arlington Capital View, Arlington VA
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** QIBA locates, encourages, and if necessary coordinates, getting the research completed so the profile can proceed
'''[http://www2.rsna.org/re/QIBA_Annual_Meeting_2011/ Presentations]'''
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----
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NEW: '''[[How To's| "How To" help pages]]'''
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*[[Media:Enabling E-alerts-20100504.pdf|Enabling E-alerts]]
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*[[Media:Microsoft Word - WIKI PROTOCOL-v2.pdf|Posting Material]]
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*[[Media:Wiki Help-History Overview2.pdf|History Search]]
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'''''<This Wiki is a Work In Progress:  read [[Help:Contents|Help]], create an [[Wiki Accounts|account]], contribute>'''''
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Revision as of 22:04, 19 August 2011

__

  • A Profile is a document.


  • It tells a user what can be accomplished by following the Profile. ("Profile Claims")
E.g. you will be able to detect volume changes of greater than <20%> in Stage IV Lung Nodules which are <5mm> in diameter or greater.


  • It tells a vendor what they must implement in their product to state compliance with the Profile. ("Profile Details")
E.g. to comply, the scanner must be able to:
  • scan a <Mark-324> Chest Phantom, identify the smallest resolvable target, display the diameter of that target
  • demonstrate resolving targets at least as small as <2mm> diameter on the Mark-324 phantom
  • scan patients according to the ACRIN NLST acquisition protocol
E.g. to comply, the quantification application must be able to:
  • segment a nodule (automatically or manually), derive the volume, store it in a DICOM object
  • run a user through a set of test data with known volumes and at the end display an accuracy score


  • It may also tell the user staff what they must do for the Profile Claims to be realized. ("Profile Details")
E.g. to comply, the site CT techs must be able to:
  • scan the patient within 10 minutes of contrast injection
E.g. to comply, the radiologist must be able to:
  • achieve a score of <95%> or better using their segmentation application on the <Lung Invaders> test set.


How do Profiles fit in the IHE Process?

The Profile concept and process has been borrowed from IHE

  • Users identify a high priority multi-system problem.
  • Vendors & Users collaborate to document a standards-based solution (a Profile).
  • Vendors confirm it works by testing their implementations with other vendors (a Connectathon)


How does QIBA differ from IHE?

  • IHE mostly profiles engineering problems. QIBA also tackles scientific problems.
  • When a profile claim is unvalidated or a profile detail cannot be defined until further research is done:
    • IHE declares the profile premature and sets it aside until such groundwork is completed
    • QIBA locates, encourages, and if necessary coordinates, getting the research completed so the profile can proceed