Difference between revisions of "VolCT - Group 1A"
Jump to navigation
Jump to search
Line 15: | Line 15: | ||
*[[Media:QIBA_VolCT_1A_Project_Timeline_2009-01-26.doc |2002-01-26: 1A Reader Study timeline for completion 1/1-4/15/2009- Please edit/comment]] | *[[Media:QIBA_VolCT_1A_Project_Timeline_2009-01-26.doc |2002-01-26: 1A Reader Study timeline for completion 1/1-4/15/2009- Please edit/comment]] | ||
*[[Media:QIBA-slicedata-medium-detailed-2009-02-02.ppt|2009-02-02: Examples of Philips Medium and Detailed reconstruction filter slices- Please review/vote on appropriate filtering for 1A study]] | *[[Media:QIBA-slicedata-medium-detailed-2009-02-02.ppt|2009-02-02: Examples of Philips Medium and Detailed reconstruction filter slices- Please review/vote on appropriate filtering for 1A study]] | ||
− | *[[Media:QIBA-slicedata-detailed-2009-01-28.ppt|2009-02-02: 1A study 40 nodule slice date- 10mm ellipse -> 20 mm ellipse] | + | *[[Media:QIBA-slicedata-detailed-2009-01-28.ppt|2009-02-02: 1A study 40 nodule slice date- 10mm ellipse -> 20 mm ellipse]] |
== Projects == | == Projects == |
Revision as of 15:03, 2 February 2009
Current Goals & Status:
- Goal: Benchmark intra/inter-reader variability for lung nodule volume measurements
- Status: Most of Dataset acquired; finalizing reader software
- Related Profile: Lung Vol Quantification - Measurement Activity
Work Documents
- Vol-CT - 1A Group Call Summaries
- Proposed 1A Protocol Outline (2008-11-13-v05)- For Comment from QIBA Members
- ---- Comments Bob Ford 12/16/2008
- RSNA Abstract SSK04-04: phantom study simialr to our proposal- For discussion on 12/18/2008 1A t-con.
- 2002-01-26: 1A Reader Study timeline for completion 1/1-4/15/2009- Please edit/comment
- 2009-02-02: Examples of Philips Medium and Detailed reconstruction filter slices- Please review/vote on appropriate filtering for 1A study
- 2009-02-02: 1A study 40 nodule slice date- 10mm ellipse -> 20 mm ellipse
Projects
May want to split these out to separate pages later
VolCT Lung Anthropomorphic Phantom Study
Objective:
Measure intra- & inter-reader bias and variability phantom lesions for:
- Uni-dimensional size measurement
- Semi-automatic 3D volumetric measure
May compare with fully automated algorithm(s)
Dataset:
Ground truth has been established by physical measurement "ex vivo“ on FDA phantom inserts.
Nodules (10 attached nodules)
- -10 & +100HU
- 10, 20 mm spheres
- 10 mm ovoid, lobulated, spiculated
Image Dataset
- 100 mAs exposures
- 0.75 & 5.0 mm slices
- 1 recon kernel
- Status:
- mostly acquired by FDA/CDRH/OSEL.
- Missing: 10 mm ovoid, spic, lob (Est: 12/01/08)
Acquisition Protocol:
- Scanner: Philips 16 slice
- Exposure (120 kVp): 100 mAs
- Slice thickness (50% overlap): 0.75 & 5.0 mm slices
- Recon kernel: Standard/medium (Still on table: Detail/Lung kernel)
- Pitch: 1.2
- 2 repeat scans
- 40 segmentations in set
The study is being conducted as a pilot. The size (data, readers) has not been selected for any specific level of significance.
Study Protocol:
Expert readers will measure/estimate nodule size from CT images.
Readers: 6 RadPharm radiologists
Software:
- Wendy will visit RadPharm and provide more info next week
- In-house review software (Siemens?)
- Semi-automated 3D volume software
- Uni-dimensional measure (RESIST)
- Which fully automated software?
Reading Session:
- Readers read all cases in 2 different reading sessions
- Random ordering
- One-dimensional measure
- Semi-automated segmentation
- Sessions separated by 3 week(?)
- Include duplicate cases within each read session (1/3-1/2 of cases for intra-reader estimates)
- Random ordering
- Time restrictions: Probably not (?)
- Specific instructions: Probably not (?)
- Readers read all cases in 2 different reading sessions
Analysis:
Estimate intra- and inter-reader variability in the different volume estimate
- Estimate bias from known truth
- Estimate variability
Compare the bias and variability with the different methods