Difference between revisions of "VolCT - Group 1A"
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*[[Vol-CT - 1A Group Call Summaries]] | *[[Vol-CT - 1A Group Call Summaries]] | ||
*[[Media:Qiba-nxp-ProposedPhase1A-2008-11-13-v05.ppt|Proposed 1A Protocol Outline (2008-11-13-v05)- For Comment from QIBA Members]] | *[[Media:Qiba-nxp-ProposedPhase1A-2008-11-13-v05.ppt|Proposed 1A Protocol Outline (2008-11-13-v05)- For Comment from QIBA Members]] | ||
+ | *[[Media:Rsna2009-ssk04-04-PhantomReaderStudy.doc|RSNA Abstract SSK04-04: phantom study simialr to our proposal- For discussion on 12/18/2008 1A t-con.]] | ||
== Projects == | == Projects == |
Revision as of 20:25, 15 December 2008
Current Goals & Status:
- Goal: Benchmark intra/inter-reader variability for lung nodule volume measurements
- Status: Most of Dataset acquired; finalizing reader software
- Related Profile: Lung Vol Quantification - Measurement Activity
Work Documents
- Vol-CT - 1A Group Call Summaries
- Proposed 1A Protocol Outline (2008-11-13-v05)- For Comment from QIBA Members
- RSNA Abstract SSK04-04: phantom study simialr to our proposal- For discussion on 12/18/2008 1A t-con.
Projects
May want to split these out to separate pages later
VolCT Lung Anthropomorphic Phantom Study
Objective:
Measure intra- & inter-reader bias and variability phantom lesions for:
- Uni-dimensional size measurement
- Semi-automatic 3D volumetric measure
May compare with fully automated algorithm(s)
Dataset:
Ground truth has been established by physical measurement "ex vivo“ on FDA phantom inserts.
Nodules (10 attached nodules)
- -10 & +100HU
- 10, 20 mm spheres
- 10 mm ovoid, lobulated, spiculated
Image Dataset
- 100 mAs exposures
- 0.75 & 5.0 mm slices
- 1 recon kernel
- Status:
- mostly acquired by FDA/CDRH/OSEL.
- Missing: 10 mm ovoid, spic, lob (Est: 12/01/08)
Acquisition Protocol:
- Scanner: Philips 16 slice
- Exposure (120 kVp): 100 mAs
- Slice thickness (50% overlap): 0.75 & 5.0 mm slices
- Recon kernel: Standard/medium (Still on table: Detail/Lung kernel)
- Pitch: 1.2
- 2 repeat scans
- 40 segmentations in set
The study is being conducted as a pilot. The size (data, readers) has not been selected for any specific level of significance.
Study Protocol:
Expert readers will measure/estimate nodule size from CT images.
Readers: 6 RadPharm radiologists
Software:
- Wendy will visit RadPharm and provide more info next week
- In-house review software (Siemens?)
- Semi-automated 3D volume software
- Uni-dimensional measure (RESIST)
- Which fully automated software?
Reading Session:
- Readers read all cases in 2 different reading sessions
- Random ordering
- One-dimensional measure
- Semi-automated segmentation
- Sessions separated by 3 week(?)
- Include duplicate cases within each read session (1/3-1/2 of cases for intra-reader estimates)
- Random ordering
- Time restrictions: Probably not (?)
- Specific instructions: Probably not (?)
- Readers read all cases in 2 different reading sessions
Analysis:
Estimate intra- and inter-reader variability in the different volume estimate
- Estimate bias from known truth
- Estimate variability
Compare the bias and variability with the different methods