Difference between revisions of "QIBA for Statisticians"

From QIBA Wiki
Jump to: navigation, search
(Created page with "'''QIBA Mission: Improve the value and practicality of quantitative imaging biomarkers by reducing variability across devices, sites, patients, and time.''' QIBA develops P...")
 
Line 8: Line 8:
 
* understanding the role of technical performance characteristics in quantifying change in individual patients
 
* understanding the role of technical performance characteristics in quantifying change in individual patients
 
* (being provided with good estimates of the technical performance of QIBs obtained using a given QIBA Profile)
 
* (being provided with good estimates of the technical performance of QIBs obtained using a given QIBA Profile)
 +
  
 
Statisticians '''participate''' in QIBA Profiles by:
 
Statisticians '''participate''' in QIBA Profiles by:
 
* supporting testing of actors’ conformance with requirements in a given QIBA Profile
 
* supporting testing of actors’ conformance with requirements in a given QIBA Profile
 +
  
 
Statisticians may also '''consider''':
 
Statisticians may also '''consider''':

Revision as of 00:17, 4 September 2019

QIBA Mission: Improve the value and practicality of quantitative imaging biomarkers by reducing variability across devices, sites, patients, and time.

QIBA develops Profile documents that standardize methods for creating a specific biomarker with predictable performance (accuracy and reproducibility).


Statisticians benefit from QIBA by:

  • understanding the role of technical performance characteristics (repeatability, reproducibility, bias, linearity) in the study design and analysis of clinical trials with quantitative imaging biomarkers (QIBs)
  • understanding the role of technical performance characteristics in quantifying change in individual patients
  • (being provided with good estimates of the technical performance of QIBs obtained using a given QIBA Profile)


Statisticians participate in QIBA Profiles by:

  • supporting testing of actors’ conformance with requirements in a given QIBA Profile


Statisticians may also consider:

  • optimizing study design in clinical trials with QIBs
  • determining sample size calculations for clinical trials using QIBs
  • providing unbiased estimates of treatment effects when QIBs are endpoints